QDoes5-HTPrelease growth hormone like tryptophan does?
AAsignificanteffect on growth hormone release in humans after oral ingestion of 2 grams ofL-tryptophanhas been demonstrated.1I would expect a similar rise with 50-100 mg of 5-HTP. Furthermore, there is evidence that melatonin may enhance growth hormonesecretion,2-3and5-HTPis a precursor of serotonin and melatonin. So although the data are not conclusive with regard to tryptophan and growth hormone, I believe that tryptophan and5-HTPprobably significantly enhance the release of growth hormone in humans.
Hyyppa MT, Jolma T, Liira J, Langvik VA, Kytomaki O. L-tryptophan treatment and the episodic secretion of pituitary hormones and cortisol.Psychoneuroendocrinology1979;4:29-35.
Smythe, G.A., and Lazarus, L. Growth hormone regulation by melatonin and serotonin.Nature1973;244:230-231.
Valcavi R, Zini M, Maestroni G, and Conti A. Melatonin stimulates growth hormone secretion through pathways other than the growth-hormone releasing hormone.Clinical Endocrinology1993;39:193-199.
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