Really Make the Difference!

Some Dietary Supplements for Men Are Not Just Nostrums

With regular use, dietary supplements may make you all the man you can be, in the post-drug, loaded sense of that phrase. And also take you to places that are not on the itinerary of a certain highly touted drug. That is because there are health products with a broad spectrum of benefits intended to take you back to where you were before sexual dysfunction entered your vocabulary.

The ingredients mentioned below may be chosen to provide benefits beyond erectile function and enhancement of libido. All are backed by scientific studies that indicate effects ranging from cognitive increases to mental fitness to robust well-being. A drug is not the final word. We want a holistic state of health, where sexual energy is but one beautiful part of an integrated life.

Arginine is an amino acid that may be the single most important nutrient you can take (see the preceding article in this issue). In addition to its myriad benefits in many aspects of human physiology, arginine is the precursor of nitric oxide, a vasodilator that plays a vital role in providing ample blood flow to the penis (and, for that matter, to the clitoris and vagina in women).


These ingredients have been shown not only to improve sexual function in men, but also to enhance many aspects of their health.



  1. Mitra SK, Chakraborti A, Bhattacharya SK. Neuropharmacological studies on Panax ginseng. Indian J Exp Biol 1996 Jan;34(1):41-7.
  2. Gillis CN. Panax ginseng pharmacology: a nitric oxide link? Biochem Pharmacol1997 Jul 1;54(1):1-8.
  3. Schultes RE, Raffauf RF. The Healing Forest. Medicinal and Toxic Plants of the Northwest Amazonia. Dioscorides Press, Portland, OR, 1990.
  4. Hindmarch I. Activity of Ginkgo biloba extract on short-term memory. Presse Med1986 Sep 25;15(31):1592-4.
  5. Cohen AJ, Bartlik B. Ginkgo biloba for antidepressant-induced sexual dysfunction. J Sex Marital Ther 1998 Apr-Jun;24(2):139-43.
  6. Krzeski T, Kazon M, Borkowski A, Witeska A, Kuczera J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993 Nov-Dec;15(6):1011-20.
  7. Schottner M, Gansser D, Spiteller G. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997 Dec;63(6):529-32.
  8. Hryb DJ, Khan MS, Romas NA, Rosner W. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med 1995 Feb;61(1):31-2.
  9. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991 May-Jun;33(1-2):91-5.
  10. Kupparanjan K, et al. Effect of ashwagandha on the process of aging in human volunteers. J Res Ayurveda Siddha 1980;1:247-58.
  11. Schmidt K, Geckeler K. Pharmacotherapy with Avena sativa - a double blind study. Int J Clin Pharmacol Biopharm 1976 Oct;14(3):214-6.
  12. McIlvenna T. Institute for Advanced Study of Human Sexuality:
  13. Kruse CA. Treatment of fatigue with aspartic acid salts. Northwest Med1961;60:597.
  14. Shaw DL, Chesney MA, Tullis IF, Agersborg MPK. Management of fatigue: a physiological approach. Am J Med Sci 1962;243:758.
  15. Ahlborg B, Ekelund LG, Nilsson CG. Effect of potassium-magnesium aspartate on the capacity for prolonged exercise in man. Acta Physiol Scand 1968;74:238.
  16. Wesson M, McNaughton L, Davies P, Tristram S. Effects of oral administration of aspartic acid salts on the endurance capacity of trained athletes. Res Q Exercise Sport 1988;59:234.
  17. Gupta GS, Srivastava KK. Effect of potassium-magnesium aspartate on endurance work in man. Ind J Exp Biol 1973;11:392.
  18. Hunt CD, Johnson PE, Herbel J, Mullen LK. Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men. Am J Clin Nutr 1992 Jul;56(1):148-57.
  19. Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ. Zinc status and serum testosterone levels of healthy adults. Nutrition 1996 May;12(5):344-8.
  20. Bordin D, Sartorelli L, Bonanni G, Mastrogiacomo I, Scalco E. High intensity physical exercise induced effects on plasma levels of copper and zinc. Biol Trace Elem Res 1993 Feb;36(2):129-34.
  21. Schuschke DA. Dietary copper in the physiology of the microcirculation. J Nutr1997 Dec;127(12):2274-81.
  22. Maiorino M, Wissing JB, Brigelius-Flohe R, Calabrese F, Roveri A, Steinert P, Ursini F, Flohe L. Testosterone mediates expression of the selenoprotein PHGPx by induction of spermatogenesis and not by direct transcriptional gene activation. FASEB J 1998 Oct;12(13):1359-70.
  23. Scott R, MacPherson A, Yates RW, Hussain B, Dixon J. The effect of oral selenium supplementation on human sperm motility. Br J Urol 1998 Jul;82(1):76-80.
  24. Blanco R, Saenz de Tejada I, Goldstein I, Krane RJ, Wotiz HH, Cohen RA. Dysfunctional penile cholinergic nerves in diabetic impotent men. J Urol 1990 Aug;144(2 Pt 1):278-80.